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An extended cell-based smoothed discrete shear gap method (XCS-FEM-DSG3) for free vibration analysis
M. H. NGUYEN-THOI,L. Le-ANH,V. Ho-HUU,H. Dang-TRUNG,T. NGUYEN-THOI
《结构与土木工程前沿(英文)》 2015年 第9卷 第4期 页码 341-358 doi: 10.1007/s11709-015-0302-1
关键词: cracked Reissner-Mindlin shell free vibration analysis cell-based smoothed discrete shear gap method (CS-FEM-DSG3) extended cell-based smoothed discrete shear gap method (XCS-FEM-DSG3) smoothed finite element methods (SFEM)
Nhan NGUYEN-MINH, Nha TRAN-VAN, Thang BUI-XUAN, Trung NGUYEN-THOI
《结构与土木工程前沿(英文)》 2019年 第13卷 第2期 页码 251-272 doi: 10.1007/s11709-017-0456-0
关键词: homogenization corrugated panel asymptotic analysis smoothed finite element method (S-FEM) cell-based smoothed three-node Mindlin plate element (CS-MIN3)
Gui-Rong Liu
《结构与土木工程前沿(英文)》 2019年 第13卷 第2期 页码 456-477 doi: 10.1007/s11709-019-0519-5
The smoothed finite element method (S-FEM) was originated by G R Liu by combining some meshfree techniques with the well-established standard finite element method (FEM). It has a family of models carefully designed with innovative types of smoothing domains. These models are found having a number of important and theoretically profound properties. This article first provides a concise and easy-to-follow presentation of key formulations used in the S-FEM. A number of important properties and unique features of S-FEM models are discussed in detail, including 1) theoretically proven softening effects; 2) upper-bound solutions; 3) accurate solutions and higher convergence rates; 4) insensitivity to mesh distortion; 5) Jacobian-free; 6) volumetric-locking-free; and most importantly 7) working well with triangular and tetrahedral meshes that can be automatically generated. The S-FEM is thus ideal for automation in computations and adaptive analyses, and hence has profound impact on AI-assisted modeling and simulation. Most importantly, one can now purposely design an S-FEM model to obtain solutions with special properties as wish, meaning that S-FEM offers a framework for design numerical models with desired properties. This novel concept of numerical model on-demand may drastically change the landscape of modeling and simulation. Future directions of research are also provided.
关键词: computational method finite element method smoothed finite element method strain smoothing technique smoothing domain weakened weak form solid mechanics softening effect upper bound solution
《化学科学与工程前沿(英文)》 2022年 第16卷 第6期 页码 874-885 doi: 10.1007/s11705-021-2131-1
关键词: discrete element method cohesive materials parameter calibration ring shear cell design of experiments
The regulatory sciences for stem cell-based medicinal products
null
《医学前沿(英文)》 2014年 第8卷 第2期 页码 190-200 doi: 10.1007/s11684-014-0323-5
Over the past few years, several new achievements have been made from stem cell studies, many of which have moved up from preclinical stages to early, or from early to middle or late, stages thanks to relatively safe profile and preliminary evidence of effectiveness. Moreover, some stem cell-based products have been approved for marketing by different national regulatory authorities. However, many critical issues associated mainly with incomplete understanding of stem cell biology and the relevant risk factors, and lack of effective regulations still exist and need to be urgently addressed, especially in countries where establishment of appropriate regulatory system just commenced. More relevantly, the stem cell regulatory sciences need to be established or improved to more effectively evaluate quality, safety and efficacy of stem cell products, and for building up the appropriate regulatory framework. In this review, we summarize some new achievements in stem cell studies, especially the preclinical and clinical studies, the existing regulations, and the associated challenges, and we then propose some considerations for improving stem cell regulatory sciences with a goal of promoting the steadfast growth of the well-regulated stem cell therapies abreast of evolvement of stem cell sciences and technologies.
关键词: stem cell-based medicinal products (SCMPs) stem cell therapy (SCT) safety effectiveness standards guidelines regulatory science
MAS-based production scheduling system for manufacturing cell-based workshop
CHU Hong-yan, CAO Quan-jun, FEI Ren-yuan
《机械工程前沿(英文)》 2006年 第1卷 第4期 页码 375-380 doi: 10.1007/s11465-006-0043-x
关键词: negotiation selection multi-agent communication abnormal
Challenges of NK cell-based immunotherapy in the new era
null
《医学前沿(英文)》 2018年 第12卷 第4期 页码 440-450 doi: tzg@ustc.edu.cn
Natural killer cells (NKs) have a great potential for cancer immunotherapy because they can rapidly and directly kill transformed cells in the absence of antigen presensitization. Various cellular sources, including peripheral blood mononuclear cells (PBMCs), stem cells, and NK cell lines, have been used for producing NK cells. In particular, NK cells that expanded from allogeneic PBMCs exhibit better efficacy than those that did not. However, considering the safety, activities, and reliability of the cell products, researchers must develop an optimal protocol for producing NK cells from PBMCs in the manufacture setting and clinical therapeutic regimen. In this review, the challenges on NK cell-based therapeutic approaches and clinical outcomes are discussed.
关键词: natural killer cells immunotherapy adoptive transfer genetic modification immune checkpoint inhibitor
Concurrent fatigue crack growth simulation using extended finite element method
Zizi LU, Yongming LIU,
《结构与土木工程前沿(英文)》 2010年 第4卷 第3期 页码 339-347 doi: 10.1007/s11709-010-0078-2
关键词: small time scale model extended finite element method (X-FEM) crack growth multiaxial
3D finite element method (FEM) simulation of groundwater flow during backward erosion piping
Kristine VANDENBOER,Vera van BEEK,Adam BEZUIJEN
《结构与土木工程前沿(英文)》 2014年 第8卷 第2期 页码 160-166 doi: 10.1007/s11709-014-0257-7
关键词: backward erosion piping groundwater flow 3D finite element method (FEM)
3D mode discrete element method with the elastoplastic model
Wei HU, Feng JIN, Chong ZHANG, Jinting WANG
《结构与土木工程前沿(英文)》 2012年 第6卷 第1期 页码 57-68 doi: 10.1007/s11709-012-0139-9
关键词: mode discrete element method elastoplastic numerical method discontinuum contact
A dynamic model of mobile concrete pump boom based on discrete time transfer matrix method
Wu REN, Yunxin WU, Zhaowei ZHANG
《机械工程前沿(英文)》 2013年 第8卷 第4期 页码 360-366 doi: 10.1007/s11465-013-0280-8
Mobile concrete pump boom is typical multi-body large-scale motion manipulator. Due to posture constantly change in working process, kinematic rule and dynamic characteristic are difficult to solve. A dynamics model of a mobile concrete pump boom is established based on discrete time transfer matrix method (DTTMM). The boom system is divided into sub-structure A and sub-structure B. Sub-structure A is composed by the 1st boom and hydraulic actuator as well as the support. And sub-structure B is consists of the other three booms and corresponding hydraulic actuators. In the model, the booms and links are regarded as rigid elements and the hydraulic cylinders are equivalent to spring-damper. The booms are driven by the controllable hydraulic actuators. The overall dynamic equation and transfer matrix of the model can be assembled by sub-structures A and B. To get a precise result, step size and integration parameters are studied then. Next the tip displacement is calculated and compared with the result of ADAMS software. The displacement and rotation angle curves of the proposed method fit well with the ADAMS model. Besides it is convenient in modeling and saves time. So it is suitable for mobile concrete pump boom real-time monitoring and dynamic analysis. All of these provide reference to boom optimize and engineering application of such mechanisms.
关键词: multi-body mobile concrete pump boom discrete time transfer matrix method (DTTMM) kinematic dynamic tip displacement
FEM-based strain analysis study for multilayer sheet forming process
Rongjing ZHANG,Lihui LANG,Rizwan ZAFAR
《机械工程前沿(英文)》 2015年 第10卷 第4期 页码 373-379 doi: 10.1007/s11465-015-0371-9
Fiber metal laminates have many advantages over traditional laminates (e.g., any type of fiber and resin material can be placed anywhere between the metallic layers without risk of failure of the composite fabric sheets). Furthermore, the process requirements to strictly control the temperature and punch force in fiber metal laminates are also less stringent than those in traditional laminates. To further explore the novel method, this study conducts a finite element method-based (FEM-based) strain analysis on multilayer blanks by using the 3A method. Different forming modes such as wrinkling and fracture are discussed by using experimental and numerical studies. Hydroforming is used for multilayer forming. The Barlat 2000 yield criteria and DYNAFORM/LS-DYNA are used for the simulations. Optimal process parameters are determined on the basis of fixed die-binder gap and variable cavity pressure. The results of this study will enhance the knowledge on the mechanics of multilayer structures formed by using the 3A method and expand its commercial applications.
关键词: finite element method (FEM) strain analysis multilayer sheet forming
Ying YAN, Pengfei LI, Shunying JI
《结构与土木工程前沿(英文)》 2013年 第7卷 第1期 页码 50-54 doi: 10.1007/s11709-013-0186-x
关键词: granular matter impact peak buffer capacity discrete element method critical thickness
Thermo-elastic extended meshfree method for fracture without crack tip enrichment
A. ASADPOUR
《结构与土木工程前沿(英文)》 2015年 第9卷 第4期 页码 441-447 doi: 10.1007/s11709-015-0319-5
Danhui DAN, Qianqing WANG, Jiongxin GONG
《结构与土木工程前沿(英文)》 2021年 第15卷 第1期 页码 244-252 doi: 10.1007/s11709-021-0696-x
关键词: granular material vibration control discrete element method particle damper cable vibration
标题 作者 时间 类型 操作
An extended cell-based smoothed discrete shear gap method (XCS-FEM-DSG3) for free vibration analysis
M. H. NGUYEN-THOI,L. Le-ANH,V. Ho-HUU,H. Dang-TRUNG,T. NGUYEN-THOI
期刊论文
Static analysis of corrugated panels using homogenization models and a cell-based smoothed mindlin plateelement (CS-MIN3)
Nhan NGUYEN-MINH, Nha TRAN-VAN, Thang BUI-XUAN, Trung NGUYEN-THOI
期刊论文
The smoothed finite element method (S-FEM): A framework for the design of numerical models for desired
Gui-Rong Liu
期刊论文
A “Sequential Design of Simulations” approach for exploiting and calibrating discrete element simulations
期刊论文
MAS-based production scheduling system for manufacturing cell-based workshop
CHU Hong-yan, CAO Quan-jun, FEI Ren-yuan
期刊论文
Concurrent fatigue crack growth simulation using extended finite element method
Zizi LU, Yongming LIU,
期刊论文
3D finite element method (FEM) simulation of groundwater flow during backward erosion piping
Kristine VANDENBOER,Vera van BEEK,Adam BEZUIJEN
期刊论文
3D mode discrete element method with the elastoplastic model
Wei HU, Feng JIN, Chong ZHANG, Jinting WANG
期刊论文
A dynamic model of mobile concrete pump boom based on discrete time transfer matrix method
Wu REN, Yunxin WU, Zhaowei ZHANG
期刊论文
FEM-based strain analysis study for multilayer sheet forming process
Rongjing ZHANG,Lihui LANG,Rizwan ZAFAR
期刊论文
Buffer capacity of granular matter to impact of spherical projectile based on discrete element method
Ying YAN, Pengfei LI, Shunying JI
期刊论文